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Tylvalosin tartrate

CAS No. 63428-13-7

Tylvalosin tartrate( Acetylisovaleryltylosin Tartrate )

Catalog No. M27525 CAS No. 63428-13-7

Tylvalosin tartrate is a macrolide antibiotic that can against Gram-positive bacteria.

Purity : >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
Size Price / USD Stock Quantity
25MG 39 In Stock
50MG 56 In Stock
100MG 80 In Stock
200MG 119 In Stock
500MG 200 In Stock
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Biological Information

  • Product Name
    Tylvalosin tartrate
  • Note
    Research use only, not for human use.
  • Brief Description
    Tylvalosin tartrate is a macrolide antibiotic that can against Gram-positive bacteria.
  • Description
    Tylvalosin tartrate is a macrolide antibiotic that can against Gram-positive bacteria.
  • In Vitro
    Apoptosis Analysis Cell Line:Porcine neutrophils Concentration:0.1, 1.0, or 10 μg/mL Incubation Time:0.5, 1 h Result:Resulted induction of concentration- and time-dependent apoptosis in porcine monocyte-derived macrophages.
  • In Vivo
    Animal Model:PRRSV-free commercial breed piglets Dosage:800 mg/kg Aivlosin (20% Tylvalosin Tartrate Premix)Administration: po; 7-14 days Result:Attenuated the increase in total white blood cells induced by immunization at day one post-immunization (DPI) and induced an increase in monocyte counts after seven DPI.Attenuate the reduction in the percentage of CD8+ T cells induced by PRRSV-inactivated vaccine immunization at seven DPI.
  • Synonyms
    Acetylisovaleryltylosin Tartrate
  • Pathway
    GPCR/G Protein
  • Target
    Antibacterial
  • Recptor
    BRD4 (1)
  • Research Area
    ——
  • Indication
    ——

Chemical Information

  • CAS Number
    63428-13-7
  • Formula Weight
    1192.34
  • Molecular Formula
    C57H93NO25
  • Purity
    >98% (HPLC)
  • Solubility
    In Vitro:?DMSO : 100 mg/mL (83.87 mM)
  • SMILES
    O[C@@H](C(O)=O)[C@H](C(O)=O)O.CC[C@H]1OC(C[C@H]([C@@H]([C@H]([C@H](C[C@H](C(/C=C\C(C)=C/[C@@H]1CO[C@@H]2O[C@@H]([C@H]([C@H]([C@H]2OC)OC)O)C)=O)C)CC=O)O[C@@H]3O[C@@H]([C@H]([C@H](N(C)C)[C@H]3O)O[C@@H]4C[C@H]([C@@H]([C@](O)(O4)C)OC(CC(C)C)=O)C)C)C)OC(C)=O)=O
  • Chemical Name
    ——

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

1.Zhang M, et al. Structure-Based Discovery and Optimization of Benzo[ d]isoxazole Derivatives as Potent and Selective BET Inhibitors for Potential Treatment of Castration-Resistant Prostate Cancer (CRPC). J Med Chem. 2018 Apr 12;61(7):3037-3058.
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